BRAF p.Val600Glu (V600E) Mutation Status for Hairy Cell Leukaemia (Accredited)

Publications have shown that all cases of Hairy Cell Leukaemia harbour the BRAF V600E variant. The analysis of BRAF V600E is a useful tool in the differential diagnosis of mature B-cell neoplasms.  


In this programme, participants are provided with lyophilised cell-lines for BRAF V600E mutation status analysis. Participants are asked to submit qualitative results, together with details of the methodology. Instructions for storage, reconstitution and use of the lyophilised samples are included with the samples. Three send-outs are issued per annum, with each send-out consisting of two samples. 


Periodically we give laboratories the option of returning quantitative results. Whilst this allows participants to compare their results with the trial statistics, it is not currently a compulsory part of the programme, nor is it subject to performance monitoring.


Trials for this programme are live/open for a minimum of 4 weeks.

Please Note: Trials issued/closing in August or December are extended by 1 week.

An automated email is sent 2 days prior to the trial closing, to any participant that has not returned results, warning them of the trial closure date. 


Pre-issue and post-closure testing of samples for this programme is subcontracted, although the final decision about sample suitability lies with the EQA provider; no other activities in relation to this EQA programme are subcontracted.


To register for this programme, please click here.

Example BRAF p.Val600Glu (V600E) Mutation Status for Hairy Cell Leukaemia Report
BRAF 222302 Report v1.0.0.pdf
Adobe Acrobat document [868.4 KB]
BRAF p.Val600Glu (V600E) Mutation Status for Hairy Cell Leukaemia Performance Monitoring System
Molecular 477__v1.3__PREVIEW.pdf
Adobe Acrobat document [78.6 KB]
Cover Letter BRAF 242501
Cover letter BRAF 242501.pdf
Adobe Acrobat document [101.5 KB]
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Last updated 16/05/2024 © UK NEQAS for Leucocyte Immunophenotyping not to be reproduced in all or part without permission.

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